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Functional characterization of endogenous siRNA target genes in Caenorhabditis elegans

BACKGROUND: Small interfering RNA (siRNA) molecules mediate sequence specific silencing in RNA interference (RNAi), a gene regulatory phenomenon observed in almost all organisms. Large scale sequencing of small RNA libraries obtained from C. elegans has revealed that a broad spectrum of siRNAs is en...

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Detalles Bibliográficos
Autores principales: Asikainen, Suvi, Heikkinen, Liisa, Wong, Garry, Storvik, Markus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440555/
https://www.ncbi.nlm.nih.gov/pubmed/18522735
http://dx.doi.org/10.1186/1471-2164-9-270