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Splign: algorithms for computing spliced alignments with identification of paralogs

BACKGROUND: The computation of accurate alignments of cDNA sequences against a genome is at the foundation of modern genome annotation pipelines. Several factors such as presence of paralogs, small exons, non-consensus splice signals, sequencing errors and polymorphic sites pose recognized difficult...

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Detalles Bibliográficos
Autores principales: Kapustin, Yuri, Souvorov, Alexander, Tatusova, Tatiana, Lipman, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440734/
https://www.ncbi.nlm.nih.gov/pubmed/18495041
http://dx.doi.org/10.1186/1745-6150-3-20