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Splign: algorithms for computing spliced alignments with identification of paralogs
BACKGROUND: The computation of accurate alignments of cDNA sequences against a genome is at the foundation of modern genome annotation pipelines. Several factors such as presence of paralogs, small exons, non-consensus splice signals, sequencing errors and polymorphic sites pose recognized difficult...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440734/ https://www.ncbi.nlm.nih.gov/pubmed/18495041 http://dx.doi.org/10.1186/1745-6150-3-20 |