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Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism

Pgp (P-glycoprotein, MDR1, ABCB1) is an energy-dependent drug efflux pump that is a member of the ATP-binding cassette (ABC) family of proteins. Preliminary studies have reported that nonspecific inhibitors of Pgp affect synthesis and esterification of cholesterol, putatively by blocking trafficking...

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Detalles Bibliográficos
Autores principales: Thornton, Sheila J, Wong, Evelyn, Lee, Stephen D, Wasan, Kishor M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440743/
https://www.ncbi.nlm.nih.gov/pubmed/18547429
http://dx.doi.org/10.1186/1476-511X-7-21