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Deferiprone targets aconitase: Implication for Friedreich's ataxia treatment
BACKGROUND: Friedreich ataxia is a neurological disease originating from an iron-sulfur cluster enzyme deficiency due to impaired iron handling in the mitochondrion, aconitase being particularly affected. As a mean to counteract disease progression, it has been suggested to chelate free mitochondria...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440763/ https://www.ncbi.nlm.nih.gov/pubmed/18558000 http://dx.doi.org/10.1186/1471-2377-8-20 |