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Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions

BACKGROUND: The tumor-initiating capacity of many cancers is considered to reside in a small subpopulation of cells (cancer stem cells). We have previously shown that rare prostate epithelial cells with a CD133(+)/α(2)β(1)(hi )phenotype have the properties of prostate cancer stem cells. We have comp...

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Detalles Bibliográficos
Autores principales: Birnie, Richard, Bryce, Steven D, Roome, Claire, Dussupt, Vincent, Droop, Alastair, Lang, Shona H, Berry, Paul A, Hyde, Catherine F, Lewis, John L, Stower, Michael J, Maitland, Norman J, Collins, Anne T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441469/
https://www.ncbi.nlm.nih.gov/pubmed/18492237
http://dx.doi.org/10.1186/gb-2008-9-5-r83