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Sequence-based prediction of protein-protein interactions by means of codon usage
We introduce a novel approach to predict interaction of two proteins solely by analyzing their coding sequences. We found that similarity in codon usage is a strong predictor of protein-protein interactions and, for high specificity values, is as sensitive as the most powerful current prediction met...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441473/ https://www.ncbi.nlm.nih.gov/pubmed/18501006 http://dx.doi.org/10.1186/gb-2008-9-5-r87 |