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RNA polymerase II stalling: loading at the start prepares genes for a sprint

Stalling of RNA polymerase II near the promoter has recently been found to be much more common than previously thought. Genome-wide surveys of the phenomenon suggest that it is likely to be a rate-limiting control on gene activation that poises developmental and stimulus-responsive genes for prompt...

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Detalles Bibliográficos
Autores principales: Wu, Jia Qian, Snyder, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441479/
https://www.ncbi.nlm.nih.gov/pubmed/18466645
http://dx.doi.org/10.1186/gb-2008-9-5-220