RNA polymerase II stalling: loading at the start prepares genes for a sprint

Stalling of RNA polymerase II near the promoter has recently been found to be much more common than previously thought. Genome-wide surveys of the phenomenon suggest that it is likely to be a rate-limiting control on gene activation that poises developmental and stimulus-responsive genes for prompt...

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Detalles Bibliográficos
Autores principales: Wu, Jia Qian, Snyder, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441479/
https://www.ncbi.nlm.nih.gov/pubmed/18466645
http://dx.doi.org/10.1186/gb-2008-9-5-220
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author Wu, Jia Qian
Snyder, Michael
author_facet Wu, Jia Qian
Snyder, Michael
author_sort Wu, Jia Qian
collection PubMed
description Stalling of RNA polymerase II near the promoter has recently been found to be much more common than previously thought. Genome-wide surveys of the phenomenon suggest that it is likely to be a rate-limiting control on gene activation that poises developmental and stimulus-responsive genes for prompt expression when inducing signals are received.
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spelling pubmed-24414792008-06-28 RNA polymerase II stalling: loading at the start prepares genes for a sprint Wu, Jia Qian Snyder, Michael Genome Biol Review Stalling of RNA polymerase II near the promoter has recently been found to be much more common than previously thought. Genome-wide surveys of the phenomenon suggest that it is likely to be a rate-limiting control on gene activation that poises developmental and stimulus-responsive genes for prompt expression when inducing signals are received. BioMed Central 2008 2008-05-02 /pmc/articles/PMC2441479/ /pubmed/18466645 http://dx.doi.org/10.1186/gb-2008-9-5-220 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Review
Wu, Jia Qian
Snyder, Michael
RNA polymerase II stalling: loading at the start prepares genes for a sprint
title RNA polymerase II stalling: loading at the start prepares genes for a sprint
title_full RNA polymerase II stalling: loading at the start prepares genes for a sprint
title_fullStr RNA polymerase II stalling: loading at the start prepares genes for a sprint
title_full_unstemmed RNA polymerase II stalling: loading at the start prepares genes for a sprint
title_short RNA polymerase II stalling: loading at the start prepares genes for a sprint
title_sort rna polymerase ii stalling: loading at the start prepares genes for a sprint
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441479/
https://www.ncbi.nlm.nih.gov/pubmed/18466645
http://dx.doi.org/10.1186/gb-2008-9-5-220
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