Cargando…

Chemical carcinogens in non-enzymatic cytosine deamination: 3-isocyanatoacrylonitrile

Uracil has long been known as the main product of nitrosative cytosine deamination in aqueous solution. Recent mechanistic studies of cytosinediazonium ion suggest that the cation formed by its dediazoniation can ring-open to N-protonated (Z,s-cis)-3-isocyanatoacrylonitrile 7. Stereochemical prefere...

Descripción completa

Detalles Bibliográficos
Autores principales: Glaser, Rainer, Wu, Hong, von Saint Paul, Francisca
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441498/
https://www.ncbi.nlm.nih.gov/pubmed/16411080
http://dx.doi.org/10.1007/s00894-005-0048-0