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Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes
Resequencing genes in individuals at extremes of the population distribution constitutes a powerful and efficient strategy to identify sequence variants associated with complex traits. An excess of sequence variants at one extreme relative to the other that is not due to chance or to population stra...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441721/ https://www.ncbi.nlm.nih.gov/pubmed/18413323 http://dx.doi.org/10.1093/hmg/ddn108 |