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Long single α-helical tail domains bridge the gap between structure and function of myosin VI
Myosin VI has challenged the lever arm hypothesis of myosin movement because of its ability to take ~36-nm steps along actin with a canonical lever arm that seems to be too short to allow such large steps. Here we demonstrate that the large step of dimeric myosin VI is primarily made possible by a m...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441774/ https://www.ncbi.nlm.nih.gov/pubmed/18511944 http://dx.doi.org/10.1038/nsmb.1429 |