Snap-to-it probes: chelate-constrained nucleobase oligomers with enhanced binding specificity

We describe snap-to-it probes, a novel probe technology to enhance the hybridization specificity of natural and unnatural nucleic acid oligomers using a simple and readily introduced structural motif. Snap-to-it probes were prepared from peptide nucleic acid (PNA) oligomers by modifying each terminu...

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Detalles Bibliográficos
Autores principales: Morgan, Joel R., Lyon, Robert P., Maeda, Dean Y., Zebala, John A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441785/
https://www.ncbi.nlm.nih.gov/pubmed/18448470
http://dx.doi.org/10.1093/nar/gkn219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441785/
https://www.ncbi.nlm.nih.gov/pubmed/18448470
http://dx.doi.org/10.1093/nar/gkn219

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