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Snap-to-it probes: chelate-constrained nucleobase oligomers with enhanced binding specificity
We describe snap-to-it probes, a novel probe technology to enhance the hybridization specificity of natural and unnatural nucleic acid oligomers using a simple and readily introduced structural motif. Snap-to-it probes were prepared from peptide nucleic acid (PNA) oligomers by modifying each terminu...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441785/ https://www.ncbi.nlm.nih.gov/pubmed/18448470 http://dx.doi.org/10.1093/nar/gkn219 |