Spatial effects on the speed and reliability of protein–DNA search

Strong experimental and theoretical evidence shows that transcription factors (TFs) and other specific DNA-binding proteins find their sites using a two-mode search: alternating between three-dimensional (3D) diffusion through the cell and one-dimensional (1D) sliding along the DNA. We show that, du...

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Detalles Bibliográficos
Autores principales: Wunderlich, Zeba, Mirny, Leonid A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441786/
https://www.ncbi.nlm.nih.gov/pubmed/18453629
http://dx.doi.org/10.1093/nar/gkn173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441786/
https://www.ncbi.nlm.nih.gov/pubmed/18453629
http://dx.doi.org/10.1093/nar/gkn173

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