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Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design

Both siRNA and antisense oligodeoxynucleotides (ODNs) inhibit the expression of a complementary gene. In this study, fundamental differences in the considerations for RNA interference and antisense ODNs are reported. In siRNA and antisense ODN databases, positive correlations are observed between th...

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Detalles Bibliográficos
Autores principales: Lu, Zhi John, Mathews, David H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441788/
https://www.ncbi.nlm.nih.gov/pubmed/18483081
http://dx.doi.org/10.1093/nar/gkn266