Cargando…

DNA physical properties determine nucleosome occupancy from yeast to fly

Nucleosome positioning plays an essential role in cellular processes by modulating accessibility of DNA to proteins. Here, using only sequence-dependent DNA flexibility and intrinsic curvature, we predict the nucleosome occupancy along the genomes of Saccharomyces cerevisiae and Drosophila melanogas...

Descripción completa

Detalles Bibliográficos
Autores principales: Miele, Vincent, Vaillant, Cédric, d'Aubenton-Carafa, Yves, Thermes, Claude, Grange, Thierry
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441789/
https://www.ncbi.nlm.nih.gov/pubmed/18487627
http://dx.doi.org/10.1093/nar/gkn262