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Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing

An intricate interplay between DNA methylation and polycomb-mediated gene silencing has been highlighted recently. Here we provided evidence that Nervous System Polycomb 1 (NSPc1), a BMI1 homologous polycomb protein, plays important roles in promoting H2A ubiquitination and cooperates with DNA methy...

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Detalles Bibliográficos
Autores principales: Wu, Xudong, Gong, Yanhua, Yue, Jiping, Qiang, Boqin, Yuan, Jiangang, Peng, Xiaozhong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441805/
https://www.ncbi.nlm.nih.gov/pubmed/18460542
http://dx.doi.org/10.1093/nar/gkn243