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Genetic Immunisation by Liver Stage Antigen 3 Protects Chimpanzees against Malaria despite Low Immune Responses

BACKGROUND: The true interest of genetic immunisation might have been hastily underestimated based on overall immunogenicity data in humans and lack of parallelism with other, more classical immunisation methods. PRINCIPAL FINDINGS: Using malaria Liver Stage Antigen-3 (LSA-3), we report that genetic...

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Detalles Bibliográficos
Autores principales: Daubersies, Pierre, Ollomo, Benjamin, Sauzet, Jean-Pierre, Brahimi, Karima, Perlaza, Blanca-Liliana, Eling, Wijnand, Moukana, Hubert, Rouquet, Pierre, de Taisne, Charles, Druilhe, Pierre
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441826/
https://www.ncbi.nlm.nih.gov/pubmed/18628827
http://dx.doi.org/10.1371/journal.pone.0002659