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Genomic Instability Is Associated with Natural Life Span Variation in Saccharomyces cerevisiae
Increasing genomic instability is associated with aging in eukaryotes, but the connection between genomic instability and natural variation in life span is unknown. We have quantified chronological life span and loss-of-heterozygosity (LOH) in 11 natural isolates of Saccharomyces cerevisiae. We show...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441830/ https://www.ncbi.nlm.nih.gov/pubmed/18628831 http://dx.doi.org/10.1371/journal.pone.0002670 |