Genomic Instability Is Associated with Natural Life Span Variation in Saccharomyces cerevisiae

Increasing genomic instability is associated with aging in eukaryotes, but the connection between genomic instability and natural variation in life span is unknown. We have quantified chronological life span and loss-of-heterozygosity (LOH) in 11 natural isolates of Saccharomyces cerevisiae. We show...

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Detalles Bibliográficos
Autores principales: Qin, Hong, Lu, Meng, Goldfarb, David S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2441830/
https://www.ncbi.nlm.nih.gov/pubmed/18628831
http://dx.doi.org/10.1371/journal.pone.0002670

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