GRK5 deficiency exaggerates inflammatory changes in TgAPPsw mice

BACKGROUND: Deficiency of membrane G-protein coupled receptor (GPCR) kinase-5 (GRK5) recently has been linked to early AD pathogenesis, and has been suggested to contribute to augmented microglial activation in vitro by sensitizing relevant GPCRs. However, GRK5 deficient mice did not show any signs...

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Detalles Bibliográficos
Autores principales: Li, Longxuan, Liu, Jun, Suo, William Z
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442054/
https://www.ncbi.nlm.nih.gov/pubmed/18522748
http://dx.doi.org/10.1186/1742-2094-5-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442054/
https://www.ncbi.nlm.nih.gov/pubmed/18522748
http://dx.doi.org/10.1186/1742-2094-5-24

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