Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1

BACKGROUND: β-Amyloid precursor protein (APP) has been reported to play a role in the outgrowth of neurites from cultured neurons. Both cell-surface APP and its soluble, ectodomain cleavage product (APPs-α) have been implicated in regulating the length and branching of neurites in a variety of assay...

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Detalles Bibliográficos
Autores principales: Young-Pearse, Tracy L, Chen, Allen C, Chang, Rui, Marquez, Cesar, Selkoe, Dennis J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442059/
https://www.ncbi.nlm.nih.gov/pubmed/18573216
http://dx.doi.org/10.1186/1749-8104-3-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442059/
https://www.ncbi.nlm.nih.gov/pubmed/18573216
http://dx.doi.org/10.1186/1749-8104-3-15

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