Cargando…
Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1
BACKGROUND: β-Amyloid precursor protein (APP) has been reported to play a role in the outgrowth of neurites from cultured neurons. Both cell-surface APP and its soluble, ectodomain cleavage product (APPs-α) have been implicated in regulating the length and branching of neurites in a variety of assay...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442059/ https://www.ncbi.nlm.nih.gov/pubmed/18573216 http://dx.doi.org/10.1186/1749-8104-3-15 |