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Mechanism of nuclear factor of activated T-cells mediated FasL expression in corticosterone -treated mouse Leydig tumor cells

BACKGROUND: Fas and FasL is important mediators of apoptosis. We have previously reported that the stress levels of corticosterone (CORT, glucocorticoid in rat) increase expression of Fas/FasL and activate Fas/FasL signal pathway in rat Leydig cells, which consequently leads to apoptosis. Moreover,...

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Detalles Bibliográficos
Autores principales: Chai, Wei-Ran, Chen, Yong, Wang, Qian, Gao, Hui-Bao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442062/
https://www.ncbi.nlm.nih.gov/pubmed/18547442
http://dx.doi.org/10.1186/1471-2121-9-31