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Differential Interactions of Na(+) Channel Toxins with T-type Ca(2+) Channels

Two types of voltage-dependent Ca(2+) channels have been identified in heart: high (I(CaL)) and low (I(CaT)) voltage-activated Ca(2+) channels. In guinea pig ventricular myocytes, low voltage–activated inward current consists of I(CaT) and a tetrodotoxin (TTX)-sensitive I(Ca) component (I(Ca(TTX)))....

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Detalles Bibliográficos
Autores principales: Sun, Hui, Varela, Diego, Chartier, Denis, Ruben, Peter C., Nattel, Stanley, Zamponi, Gerald W., Leblanc, Normand
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442173/
https://www.ncbi.nlm.nih.gov/pubmed/18591418
http://dx.doi.org/10.1085/jgp.200709883