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Amino Acid Substitutions in the Pore Helix of GluR6 Control Inhibition by Membrane Fatty Acids

RNA editing at the Q/R site in the GluR5 and GluR6 subunits of neuronal kainate receptors regulates channel inhibition by lipid-derived modulators including the cis-unsaturated fatty acids arachidonic acid and docosahexaenoic acid. Kainate receptor channels in which all of the subunits are in the ed...

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Detalles Bibliográficos
Autores principales: Wilding, Timothy J., Fulling, Elisabeth, Zhou, Yun, Huettner, James E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442176/
https://www.ncbi.nlm.nih.gov/pubmed/18562501
http://dx.doi.org/10.1085/jgp.200810009