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Amino Acid Substitutions in the Pore Helix of GluR6 Control Inhibition by Membrane Fatty Acids
RNA editing at the Q/R site in the GluR5 and GluR6 subunits of neuronal kainate receptors regulates channel inhibition by lipid-derived modulators including the cis-unsaturated fatty acids arachidonic acid and docosahexaenoic acid. Kainate receptor channels in which all of the subunits are in the ed...
Autores principales: | Wilding, Timothy J., Fulling, Elisabeth, Zhou, Yun, Huettner, James E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442176/ https://www.ncbi.nlm.nih.gov/pubmed/18562501 http://dx.doi.org/10.1085/jgp.200810009 |
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