A Close Association of RyRs with Highly Dense Clusters of Ca(2+)-activated Cl(−) Channels Underlies the Activation of STICs by Ca(2+) Sparks in Mouse Airway Smooth Muscle

Ca(2+) sparks are highly localized, transient releases of Ca(2+) from sarcoplasmic reticulum through ryanodine receptors (RyRs). In smooth muscle, Ca(2+) sparks trigger spontaneous transient outward currents (STOCs) by opening nearby clusters of large-conductance Ca(2+)-activated K(+) channels, and...

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Detalles Bibliográficos
Autores principales: Bao, Rongfeng, Lifshitz, Lawrence M., Tuft, Richard A., Bellvé, Karl, Fogarty, Kevin E., ZhuGe, Ronghua
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442178/
https://www.ncbi.nlm.nih.gov/pubmed/18591421
http://dx.doi.org/10.1085/jgp.200709933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442178/
https://www.ncbi.nlm.nih.gov/pubmed/18591421
http://dx.doi.org/10.1085/jgp.200709933

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