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Mechanosensitive Channel MscS in the Open State: Modeling of the Transition, Explicit Simulations, and Experimental Measurements of Conductance

Mechanosensitive channels of small conductance (MscS) are ubiquitous turgor pressure regulators found in many walled cells and some intracellular organelles. Escherichia coli MscS acting as a tension-activated osmolyte release valve shows a nonsaturable conductance (1.2 nS in a 39 mS/cm electrolyte)...

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Detalles Bibliográficos
Autores principales: Anishkin, Andriy, Kamaraju, Kishore, Sukharev, Sergei
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442180/
https://www.ncbi.nlm.nih.gov/pubmed/18591417
http://dx.doi.org/10.1085/jgp.200810000