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The Polycomb Repressive Complex 2 Is a Potential Target of SUMO Modifications
BACKGROUND: The Polycomb Repressive Complex 2 (PRC2) functions as a transcriptional repressor through a mechanism that involves methylation of Histone H3 at lysine 27. The PRC2 complex activity is essential for cellular proliferation, development, and cell fate decisions. PRC2 target genes include i...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442188/ https://www.ncbi.nlm.nih.gov/pubmed/18628979 http://dx.doi.org/10.1371/journal.pone.0002704 |