Identification of a Regulatory T Cell Specific Cell Surface Molecule that Mediates Suppressive Signals and Induces Foxp3 Expression

Regulatory T (T(reg)) cells control immune activation and maintain tolerance. How T(regs) mediate their suppressive function is unclear. Here we identified a cell surface molecule, called GARP, (or LRRC32), which within T cells is specifically expressed in T(regs) activated through the T cell recept...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Wan, Qi, Kozhaya, Lina, Fujii, Hodaka, Unutmaz, Derya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442191/
https://www.ncbi.nlm.nih.gov/pubmed/18628982
http://dx.doi.org/10.1371/journal.pone.0002705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442191/
https://www.ncbi.nlm.nih.gov/pubmed/18628982
http://dx.doi.org/10.1371/journal.pone.0002705

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