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Nerve Growth Factor Stimulates Interaction of Cayman Ataxia Protein BNIP-H/Caytaxin with Peptidyl-Prolyl Isomerase Pin1 in Differentiating Neurons

Mutations in ATCAY that encodes the brain-specific protein BNIP-H (or Caytaxin) lead to Cayman cerebellar ataxia. BNIP-H binds to glutaminase, a neurotransmitter-producing enzyme, and affects its activity and intracellular localization. Here we describe the identification and characterization of the...

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Detalles Bibliográficos
Autores principales: Buschdorf, Jan Paul, Chew, Li Li, Soh, Unice Jim Kim, Liou, Yih-Cherng, Low, Boon Chuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442193/
https://www.ncbi.nlm.nih.gov/pubmed/18628984
http://dx.doi.org/10.1371/journal.pone.0002686