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Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system

Rapid nerve impulse conduction in myelinated axons requires the concentration of voltage-gated sodium channels at nodes of Ranvier. Myelin-forming oligodendrocytes in the central nervous system (CNS) induce the clustering of sodium channels into nodal complexes flanked by paranodal axoglial junction...

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Detalles Bibliográficos
Autores principales: Zonta, Barbara, Tait, Steven, Melrose, Shona, Anderson, Heather, Harroch, Sheila, Higginson, Jennifer, Sherman, Diane L., Brophy, Peter J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442198/
https://www.ncbi.nlm.nih.gov/pubmed/18573915
http://dx.doi.org/10.1083/jcb.200712154