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Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast

Signaling mucins are cell adhesion molecules that activate RAS/RHO guanosine triphosphatases and their effector mitogen-activated protein kinase (MAPK) pathways. We found that the Saccharomyces cerevisiae mucin Msb2p, which functions at the head of the Cdc42p-dependent MAPK pathway that controls fil...

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Detalles Bibliográficos
Autores principales: Vadaie, Nadia, Dionne, Heather, Akajagbor, Darowan S., Nickerson, Seth R., Krysan, Damian J., Cullen, Paul J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442203/
https://www.ncbi.nlm.nih.gov/pubmed/18591427
http://dx.doi.org/10.1083/jcb.200704079