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Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast
Signaling mucins are cell adhesion molecules that activate RAS/RHO guanosine triphosphatases and their effector mitogen-activated protein kinase (MAPK) pathways. We found that the Saccharomyces cerevisiae mucin Msb2p, which functions at the head of the Cdc42p-dependent MAPK pathway that controls fil...
Autores principales: | Vadaie, Nadia, Dionne, Heather, Akajagbor, Darowan S., Nickerson, Seth R., Krysan, Damian J., Cullen, Paul J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442203/ https://www.ncbi.nlm.nih.gov/pubmed/18591427 http://dx.doi.org/10.1083/jcb.200704079 |
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