ERK5 promotes Src-induced podosome formation by limiting Rho activation

Increased Src activity, often associated with tumorigenesis, leads to the formation of invasive adhesions termed podosomes. Podosome formation requires the function of Rho family guanosine triphosphatases and reorganization of the actin cytoskeleton. In addition, Src induces changes in gene expressi...

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Detalles Bibliográficos
Autores principales: Schramp, Mark, Ying, Olivia, Kim, Tai Young, Martin, G. Steven
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442207/
https://www.ncbi.nlm.nih.gov/pubmed/18573916
http://dx.doi.org/10.1083/jcb.200801078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442207/
https://www.ncbi.nlm.nih.gov/pubmed/18573916
http://dx.doi.org/10.1083/jcb.200801078

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