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ERK5 promotes Src-induced podosome formation by limiting Rho activation
Increased Src activity, often associated with tumorigenesis, leads to the formation of invasive adhesions termed podosomes. Podosome formation requires the function of Rho family guanosine triphosphatases and reorganization of the actin cytoskeleton. In addition, Src induces changes in gene expressi...
Autores principales: | Schramp, Mark, Ying, Olivia, Kim, Tai Young, Martin, G. Steven |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442207/ https://www.ncbi.nlm.nih.gov/pubmed/18573916 http://dx.doi.org/10.1083/jcb.200801078 |
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