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A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction

People who begin daily smoking at an early age are at greater risk of long-term nicotine addiction. We tested the hypothesis that associations between nicotinic acetylcholine receptor (nAChR) genetic variants and nicotine dependence assessed in adulthood will be stronger among smokers who began dail...

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Detalles Bibliográficos
Autores principales: Weiss, Robert B., Baker, Timothy B., Cannon, Dale S., von Niederhausern, Andrew, Dunn, Diane M., Matsunami, Nori, Singh, Nanda A., Baird, Lisa, Coon, Hilary, McMahon, William M., Piper, Megan E., Fiore, Michael C., Scholand, Mary Beth, Connett, John E., Kanner, Richard E., Gahring, Lorise C., Rogers, Scott W., Hoidal, John R., Leppert, Mark F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442220/
https://www.ncbi.nlm.nih.gov/pubmed/18618000
http://dx.doi.org/10.1371/journal.pgen.1000125