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A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus

Cell-cell contacts play a vital role in intracellular signaling, although the molecular mechanisms of these signaling pathways are not fully understood. E-cadherin, an important mediator of cell-cell adhesions, has been shown to be cleaved by γ-secretase. This cleavage releases a fragment of E-cadhe...

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Detalles Bibliográficos
Autores principales: Ferber, Emma C., Kajita, Mihoko, Wadlow, Anthony, Tobiansky, Lara, Niessen, Carien, Ariga, Hiroyoshi, Daniel, Juliet, Fujita, Yasuyuki
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442316/
https://www.ncbi.nlm.nih.gov/pubmed/18356166
http://dx.doi.org/10.1074/jbc.M708887200