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Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

Parkinson's disease is a neurodegenerative disorder with uncertain aetiology and ill-defined pathophysiology. Activated microglial cells in the substantia nigra (SN) are found in all animal models of Parkinson's disease and patients with the illness. Microglia may, however, have detrimenta...

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Dettagli Bibliografici
Autori principali: Godoy, María Clara Pott, Tarelli, Rodolfo, Ferrari, Carina Cintia, Sarchi, Maria Inés, Pitossi, Fernando Juan
Natura: testo
Lingua:English
Pubblicazione: Oxford University Press 2008
Soggetti:
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442423/
https://www.ncbi.nlm.nih.gov/pubmed/18504291
http://dx.doi.org/10.1093/brain/awn101