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Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
Parkinson's disease is a neurodegenerative disorder with uncertain aetiology and ill-defined pathophysiology. Activated microglial cells in the substantia nigra (SN) are found in all animal models of Parkinson's disease and patients with the illness. Microglia may, however, have detrimenta...
Autori principali: | , , , , |
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Natura: | testo |
Lingua: | English |
Pubblicazione: |
Oxford University Press
2008
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Soggetti: | |
Accesso online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442423/ https://www.ncbi.nlm.nih.gov/pubmed/18504291 http://dx.doi.org/10.1093/brain/awn101 |