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Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells

BACKGROUND: Histone deacetylase inhibitors (HDACi) are a new class of promising anti-tumour agent inhibiting cell proliferation and survival in tumour cells with very low toxicity toward normal cells. Neuroblastoma (NB) is the second most common solid tumour in children still associated with poor ou...

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Detalles Bibliográficos
Autores principales: Mühlethaler-Mottet, Annick, Meier, Roland, Flahaut, Marjorie, Bourloud, Katia Balmas, Nardou, Katya, Joseph, Jean-Marc, Gross, Nicole
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442609/
https://www.ncbi.nlm.nih.gov/pubmed/18549473
http://dx.doi.org/10.1186/1476-4598-7-55