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A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene

BACKGROUND: Angiotensin I-converting enzyme (ACE) plays an important role in cardiovascular homeostasis. There is evidence from different ethnic groups that circulating ACE levels are influenced by a quantitative trait locus (QTL) at the ACE gene on chromosome 17. The finding of significant residual...

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Detalles Bibliográficos
Autores principales: McKenzie, Colin A, Zhu, Xiaofeng, Forrester, Terrence E, Luke, Amy, Adeyemo, Adebowale A, Bouzekri, Nourdine, Cooper, Richard S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442613/
https://www.ncbi.nlm.nih.gov/pubmed/18544166
http://dx.doi.org/10.1186/1755-8794-1-23