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Relative effects of mutability and selection on single nucleotide polymorphisms in transcribed regions of the human genome

MOTIVATION: Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation in humans. However, the factors that affect SNP density are poorly understood. The goal of this study was to estimate the relative effects of mutability and selection on SNP density in transcribed region...

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Detalles Bibliográficos
Autores principales: Gorlov, Ivan P, Gorlova, Olga Y, Amos, Christopher I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442617/
https://www.ncbi.nlm.nih.gov/pubmed/18559102
http://dx.doi.org/10.1186/1471-2164-9-292