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Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive lung disease in which fibroblasts accumulate in the alveolar wall within a type I collagen–rich matrix. Although lung fibroblasts derived from patients with IPF display durable pathological alterations in proliferative function, the m...

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Detalles Bibliográficos
Autores principales: Xia, Hong, Diebold, Deanna, Nho, Richard, Perlman, David, Kleidon, Jill, Kahm, Judy, Avdulov, Svetlana, Peterson, Mark, Nerva, John, Bitterman, Peter, Henke, Craig
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442643/
https://www.ncbi.nlm.nih.gov/pubmed/18541712
http://dx.doi.org/10.1084/jem.20080001