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Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

Increased evidence suggests that cancer-associated inflammation supports tumor growth and progression. We have previously shown that semaphorin 4D (Sema4D), a ligand produced by different cell types, is a proangiogenic molecule that acts by binding to its receptor, plexin B1, expressed on endothelia...

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Detalles Bibliográficos
Autores principales: Sierra, Jose Rafael, Corso, Simona, Caione, Luisa, Cepero, Virna, Conrotto, Paolo, Cignetti, Alessandro, Piacibello, Wanda, Kumanogoh, Atsushi, Kikutani, Hitoshi, Comoglio, Paolo Maria, Tamagnone, Luca, Giordano, Silvia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442644/
https://www.ncbi.nlm.nih.gov/pubmed/18559453
http://dx.doi.org/10.1084/jem.20072602