Endothelial-specific ablation of Serum Response Factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality

BACKGROUND: Serum response factor (SRF), a member of the MADS box family of nuclear transcription factors, plays an important role in cardiovascular development and function. Numerous studies demonstrate a central role for SRF in regulating smooth and cardiac muscle cell gene expression. Consistent...

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Detalles Bibliográficos
Autores principales: Holtz, Mary L, Misra, Ravi P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442838/
https://www.ncbi.nlm.nih.gov/pubmed/18570667
http://dx.doi.org/10.1186/1471-213X-8-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442838/
https://www.ncbi.nlm.nih.gov/pubmed/18570667
http://dx.doi.org/10.1186/1471-213X-8-65

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