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Defects in Actin Dynamics Lead to an Autoinflammatory Condition through the Upregulation of CXCL5
BACKGROUND: Destrin (DSTN) is a member of the ADF/cofilin family of proteins and is an important regulator of actin dynamics. The primary function of destrin is to depolymerize filamentous actin into its monomeric form and promote filament severing. While progress has been made in understanding the...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442876/ https://www.ncbi.nlm.nih.gov/pubmed/18628996 http://dx.doi.org/10.1371/journal.pone.0002701 |