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CXCL10(+ )T cells and NK cells assist in the recruitment and activation of CXCR3(+ )and CXCL11(+ )leukocytes during Mycobacteria-enhanced colitis

BACKGROUND: The role of Mycobacteria in the etiology of Crohn's disease (CD) has been a contentious subject for many years. Recently, our laboratory showed that spontaneous colitis in IL-10(-/- )mice is driven in part by antigens (Ags) conserved in Mycobacteria. The present study dissects some...

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Detalles Bibliográficos
Autores principales: Singh, Udai P, Singh, Rajesh, Singh, Shailesh, Karls, Russell K, Quinn, Frederick D, Taub, Dennis D, Lillard, James W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443107/
https://www.ncbi.nlm.nih.gov/pubmed/18533024
http://dx.doi.org/10.1186/1471-2172-9-25