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CXCL10(+ )T cells and NK cells assist in the recruitment and activation of CXCR3(+ )and CXCL11(+ )leukocytes during Mycobacteria-enhanced colitis
BACKGROUND: The role of Mycobacteria in the etiology of Crohn's disease (CD) has been a contentious subject for many years. Recently, our laboratory showed that spontaneous colitis in IL-10(-/- )mice is driven in part by antigens (Ags) conserved in Mycobacteria. The present study dissects some...
Autores principales: | Singh, Udai P, Singh, Rajesh, Singh, Shailesh, Karls, Russell K, Quinn, Frederick D, Taub, Dennis D, Lillard, James W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443107/ https://www.ncbi.nlm.nih.gov/pubmed/18533024 http://dx.doi.org/10.1186/1471-2172-9-25 |
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