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Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

BACKGROUND: A novel fluorescent cAMP analog (8-[Pharos-575]- adenosine-3', 5'-cyclic monophosphate) was characterized with respect to its spectral properties, its ability to bind to and activate three main isoenzymes of the cAMP-dependent protein kinase (PKA-Iα, PKA-IIα, PKA-IIβ) in vitro,...

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Detalles Bibliográficos
Autores principales: Moll, Daniela, Prinz, Anke, Brendel, Cornelia M, Berrera, Marco, Guske, Katrin, Zaccolo, Manuela, Genieser, Hans-Gottfried, Herberg, Friedrich W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443153/
https://www.ncbi.nlm.nih.gov/pubmed/18578870
http://dx.doi.org/10.1186/1471-2091-9-18